Read the summary and the most important questions on How Genes Influence Behavior | 9780199559909 | Jonathan Flint; Ralph J. Greenspan; Kenneth S. Kendler

• 1 Introduction

• What are animal studies for?

  Can provide models to test for functions of genes identified in human genetic studies

• 2 Schizophrenia

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• If Schizophrenia runs in the direct family what is the chance you will develop it too in comparison to a control?

  13 times higher

• Which two things helped with the diagnosis of schizophrenia?

  Development of clear operationalized diagnostic criteria.
  Structured psychiatric interviews.

• What is a pitfall regarding adoption studies?

  Adoptee's are often matched with certain characteristics of the parents. This is not ideal for correlation.
  The in uterus environment and pre-adoption childhood experiences.
  Adoptive parents are not generally representative.

• What idea are twin studies based on?

  That resemblance among twins results from two different sets of factors. Genes and shared environment

• When can you say something is driven by genetic factors in correlation studies?

  When the correlation of the MZ twins is at least twice as high.

• What if the magnitude of the correlation between dz/mz twins is between 50-100%?

  Probably both genetic and environment

• How do you express heritability in a ratio?

  Heritability=genetic variance/total variance

• What are some methodological concerns regarding twin studies?

  Is the equal environmental exposure really equal
  Sometimes people are misinformed about their twin status
  Are twins representative for the population since they constitute very little of the gp

• What is the heritability of schizophrenia? 

  Around 80 percent